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BioCentury 08.24.14 - [1] Impure
BioCentury 08.24.14 - [1] Impure
FDA Historian John P. Swann on 150 years of agency development. Chemist Harvey Wiley's Poison Squad and Upton Sinclair's The Jungle reveal widespread adulteration of food products leading to the 1906 Pure Food Act.
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BioCentury 08.24.14 - [2] Evidence-Based
BioCentury 08.24.14 - [2] Evidence-Based
In the early 60s, FDA scientist Frances Kelsey stands firm against approval of thalidomide, averting a national disaster; Sen. Estes Kefauver then secures legislation ensuring stronger drug review.
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BioCentury 08.24.14 - [3] Patients Lead the Way
BioCentury 08.24.14 - [3] Patients Lead the Way
Grassroots activism was a hallmark of FDA history in the 80s. AIDS protests force development of new drugs; the work of mother-advocate Abbey Meyers and TV star Jack Klugman resulted in the Orphan Drug Act.
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BioCentury 08.24.14 - [4] Responsibilities in New Century
BioCentury 08.24.14 - [4] Responsibilities in New Century
In 2004, side effects associated with Vioxx led to its recall. Increased pressure to rapidly approve safe drugs in a global environment bring forth the 2011 Modernization Act and the 2012 Safety and Innovation Act.
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